Lymphocyte Subsets and Langerhans Cells/Indeterminate Cells in Erythema Multiforme

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Erythema multiforme.

Erythema multiforme is a skin condition considered to be a hypersensitivity reaction to infections or drugs. It consists of a polymorphous eruption of macules, papules, and characteristic "target" lesions that are symmetrically distributed with a propensity for the distal extremities. There is minimal mucosal involvement. Management involves treating the existing infectious agent or discontinui...

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The aim of this work was to demonstrate, quantify and compare cell elements in the inflammatory infiltrate of 23 skin lesions of actinomycetoma (ACM) and 17 of eumycetoma (EUM). Epidermal Langerhans cells (LC) population was also analyzed in 18 ACM, 13 EUM and ten normal skin samples as control group. Tissue response in both groups of mycetoma showed CD4 and CD8 T lymphocytes surrounding the ne...

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Erythema multiforme in leprosy.

The clinical course of leprosy is often interrupted by reactions, which are acute inflammatory episodes that can be classified as type I or type II. Type II reactions can present as cutaneous lesions that resemble erythema multiforme (EM). EM is classically associated with drug allergies or pre-existing viral infections. However, the differential diagnostic criteria of the diverse causative age...

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Number IV Erythema multiforme

Erythema multiforme (EM) is an acute mucocutaneous hypersensitivity reaction characterised by a skin eruption, with or without oral or other mucous membrane lesions. Occasionally EM may involve the mouth alone. EM has been classified into a number of different variants based on the degree of mucosal involvement and the nature and distribution of the skin lesions. EM minor typically affects no m...

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Erythema Multiforme — Definition and Treatment

Erythema multiforme (EM) is a type of cytotoxic dermatitis, which can be triggered by many factors; mainly herpes simplex infection and drugs being the implicating factors. Although it is self-limiting, recurrences are common. In this article, definition, epidemiology, aetiology, pathology, pathophysiology, symptoms, diagnosis, differential diagnosis, therapy, prognosis and progression of EM wi...

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ژورنال

عنوان ژورنال: Journal of Investigative Dermatology

سال: 1983

ISSN: 0022-202X

DOI: 10.1111/1523-1747.ep12522001